Des Moines to San Francisco (DSM → SFO). We are tracking 5 fares on this route.
Cheapest tracked fare $119 · typical price $219 · you save about $100 (46%)
Cheapest fares we're tracking
Airline
Departs
Stops
Price
Frontier
2026-09-28
1 stop
$119
—
2026-10-05
1 stop
$119
—
2026-11-09
1 stop
$119
—
2026-12-03
1 stop
$119
American Airlines
2026-10-06
1 stop
$154
Could you save more?
The airport you were going to fly from is often not the cheapest one. Compare every airport in a region against each other, or check whether a multi-day stopover beats the direct fare.
How cheap can flights from Des Moines to San Francisco get?
The cheapest fare we have tracked on this route is $119, compared with a typical $219 for a trip of this distance.
Is it cheaper to fly to San Francisco from a different airport?
Often, yes. Fares out of secondary airports are frequently cheaper than the obvious hub, but they are the ones most likely to be missing from a normal search. Our reverse search compares every airport in a region against each other so the cheaper departure point is not hidden.
Could a stopover make Des Moines to San Francisco cheaper?
Sometimes. On thin long-haul routes a two-leg trip with a multi-day stopover can beat the direct fare, and occasionally a direct fare is not sold at all. Our detour search prices those routings against the direct flight.